DG is a waitress ripped out of her boring life by a cyclone that drops her into "The O.Z." (Outer Zone). She learns that this new land is beautiful and deadly, since it lies in thrall to Azkadellia, a ruthless sorceress who has seized power. All Azkadellia needs to make her conquest complete is the Emerald of the Eclipse, but the location is buried in DG's subconscious. As DG follows her dangerous path along the Old Brick Road, she is joined by brainless Glitch, troubled former lawman Wyatt Cain, and terrified oracle Raw.
Kamijou Touma is a student living in Academy City, a highly advanced place in terms of technology. Despite being gauged as a level zero esper (no powers), he possesses on his right hand the Imagine Breaker, an ability that negates any power whatsoever. Touma finds a young girl named Index who is trying to run away from Necessarius, a powerful magic organization that she is member of. Blessed with the skill of memorizing any sort of information, she holds 103,000 forbidden magical books within her head. As science and magic cross paths, Touma must face several dangers amid espers and magicians who appear at the exciting scientific town.